Why the study?
Does the Mueller maneuver affect left ventricular function in patients with coronary artery disease?
Population
31 subjects, including 14 patients with coronary artery disease, 5 patients without CAD, and 12 normal…
Comparison
Mueller maneuver vs Baseline state and subjects without CAD/normal…
Design
Cross-sectional
Authors
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Mueller maneuver may induce LV dysfunction in CAD; hypothesis-generating for sleep apnea effects, needs prospective validation.
Does the Mueller maneuver affect left ventricular function in patients with coronary artery disease?
Large negative intrathoracic pressure (Mueller maneuver) increases left ventricular afterload and can induce regional wall motion abnormalities and decrease ejection fraction in patients with CAD.
Scharf et al. (1981) studied this question.
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