Targeted therapy in cholangiocarcinoma: current landscape and future horizon

Cholangiocarcinoma (CCA) is a malignant disease of the biliary tree which accounts for 15% of primary liver cancers and 3% of gastrointestinal malignancies. For almost a decade, palliative chemotherapy remained the standard of care for advanced CCA with only modest disease control and survival rates, both in first- and second-line settings. In recent years, … Continued