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According to the “seed and soil” theory, cancer progression is influenced by the crosstalk between tumor cells and the surrounding tumor microenvironment (TME). TME comprises several cell types, including tumor-associated macrophages (TAMs), tumor-associated neutrophils (TANs), lymphocytes, leukocytes, vascular endothelial cells, pericytes, and fibroblasts.
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Faa et al. (2024) studied this question.
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