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December 18, 2003Journal of Medical Virology

Molecular characterization of coxsackievirus B5 isolates

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Population

15 strains of Coxsackievirus B5 isolated from patients with neurological disorders and healthy people

Comparison

Partial sequencing in the 5' half of the VP1… vs Other published sequences of Coxsackievirus B5…

Design

Preclinical

Authors

DRDorra RezigInstitut Pasteur de TunisAYAhlem Ben YahiaTunis UniversityHAHager Ben AbdallahAn-Najah National University

Discussion

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Implication

Supports CVB5 molecular surveillance; leaves open genotype-disease links in human myocarditis.

Structured PICO

P
Population
15 strains of Coxsackievirus B5 isolated from patients with neurological disorders and healthy people
I
Intervention
Partial sequencing in the 5' half of the VP1 region
C
Comparator
Other published sequences of Coxsackievirus B5 and prototype sequences from other Coxsackievirus B serotypes
O
Outcome
Nucleotide difference and phylogenetic clustering (genotypes)surrogate

Partial sequencing of the VP1 region is an effective method for determining the serotype and genetic characteristics of Coxsackievirus B5 isolates, revealing four distinct genotypes.

Cite This Study

Rezig et al. (2003) studied this question.

synapsesocial.com/papers/6a73f0e2f96a1419040ddadehttps://doi.org/10.1002/jmv.10579
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Also Consider

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  1. 1Reemergence of an Epidemic Coxsackievirus B5 Genotype1987 · 21 citations
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  3. 3Molecular and biological analysis of echovirus 9 strain isolated from a diabetic child2003 · 51 citations
  4. 4Diagnosis of enteroviral meningitis by using PCR with a colorimetric microwell detection assay1994 · 211 citations
  5. 5A nucleotide sequence comparison of coxsackievirus B4 isolates from aquatic samples and clinical specimens1993 · 20 citations