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May 1, 1993Journal of General Virology

Complete Nucleotide Sequence of a Coxsackie B5 Virus and its Relationship to Swine Vesicular Disease Virus

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Population

Coxsackievirus B5 (CB5), strain 1954/UK/85, an isolate from a case of hand-foot-and-mouth disease

Comparison

Nucleotide sequencing vs Other coxsackie B viruses, coxsackievirus A9…

Design

Preclinical

Authors

GZGang ZhangCentre for Human GeneticsGWGinette WilsdenThe Pirbright InstituteNKN. J. KnowlesThe Pirbright Institute

Discussion

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Implication

Indicates recombination between enteroviruses; leaves open evolutionary origins and zoonotic implications.

Structured PICO

P
Population
Coxsackievirus B5 (CB5), strain 1954/UK/85, an isolate from a case of hand-foot-and-mouth disease
I
Intervention
Nucleotide sequencing
C
Comparator
Other coxsackie B viruses, coxsackievirus A9, poliovirus and swine vesicular disease virus (SVDV)
O
Outcome
Nucleotide sequence and genetic relationship

The complete nucleotide sequence of Coxsackievirus B5 reveals a complex genetic relationship with swine vesicular disease virus, sharing closely related capsid protein genes but differing in noncoding and P3 regions.

Cite This Study

Zhang et al. (1993) studied this question.

synapsesocial.com/papers/6a7212e52163a0a01bc5ec7ehttps://doi.org/10.1099/0022-1317-74-5-845
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Variation in the Coxsackievirus Type B5 and Its Possible Role in the Etiology of Swine Vesicular Disease1974 · 31 citations
  2. 2The Complete Nucleotide Sequence of Swine Vesicular Disease Virus1989 · 74 citations
  3. 3Comparison of Swine Vesicular Disease Virus and Coxsackie B5 Virus by Serological and RNA Hybridization Methods1976 · 32 citations
  4. 4DNA sequencing with chain-terminating inhibitors1977 · 69,520 citations
  5. 5The Nucleotide Sequence of a Type 3 Poliovirus Isolated During a Recent Outbreak of Poliomyelitis in Finland1986 · 68 citations