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January 1, 1974Intervirology

Variation in the Coxsackievirus Type B5 and Its Possible Role in the Etiology of Swine Vesicular Disease

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Population

Coxsackievirus type B5 strains and swine vesicular disease virus

Design

Preclinical

Authors

FBF. BrownMaryland Institute College of ArtFWFabian WildUniversité Claude Bernard Lyon 1

Discussion

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Implication

Challenges Faulkner strain suitability as CB5 diagnostic prototype; leaves open validation of updated reference strains in clinical samples.

Structured PICO

P
Population
Coxsackievirus type B5 (CB5) strains (Faulkner strain and recent isolates) and swine vesicular disease virus (SVDV)
I
Intervention
RNA hybridization and virus neutralization tests
O
Outcome
Differences between viral strains

The Faulkner strain of coxsackievirus type B5 differs significantly from recent isolates and swine vesicular disease virus, suggesting it may not be suitable as a diagnostic prototype.

Cite This Study

Brown et al. (1974) studied this question.

synapsesocial.com/papers/6a89427aabe412682d92d418https://doi.org/10.1159/000149748
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Swine Vesicular Disease Virus and Coxsackie B5 Virus by Serological and RNA Hybridization Methods1976 · 32 citations
  2. 2Complete Nucleotide Sequence of a Coxsackie B5 Virus and its Relationship to Swine Vesicular Disease Virus1993 · 107 citations
  3. 3Attempts to infect pigs with Coxsackie virus type B51974 · 18 citations
  4. 4Molecular characterization of coxsackievirus B5 isolates2003 · 45 citations
  5. 5Molecular Aspects of the Antigenic Variation of Swine Vesicular Disease and Coxsackie B5 Viruses1977 · 30 citations