Why the study?
Does melatonin reduce arterial pressure and improve vascular pathways in spontaneously hypertensive rats?
Does melatonin reduce arterial pressure and improve vascular pathways in spontaneously hypertensive rats?
Chronic melatonin treatment exerts antihypertensive and bradycardic effects in spontaneously hypertensive rats, likely mediated by improved vascular nitric oxide synthase pathway activity.
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Melatonin shows promise in hypertensive rat models; leaves open translation to human therapy.
Girouard et al. (2001) studied this question.
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