Angiotensin II stimulates angiotensinogen release in dogs, a process that appears dependent on adrenal function and associated with corticosteroid release.
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Animal data on adrenal-dependent angiotensinogen regulation leave open human mechanistic relevance; no clinical implications.
Intravenous infusion of angiotensin II increased plasma angiotensinogen concentration in five anaesthetized dogs. 2. This increase was not a consequence of haemoconcentration but was associated with an increase in peripheral corticosteroid concentration. 3. Infusion of angiotensin II did not increase plasma angiotensinogen concentration in five adrenalectomized dogs.
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Blair‐West et al. (1974) studied this question.
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