Infection with Australian T-strain IBV impairs renal function in young male broiler chickens, and early vaccination provides only limited protection.
T-strain IBV impairs broiler renal function with limited vaccine protection; leaves open optimal control strategies in commercial poultry.
The acute effects of challenge with Australian T-strain infectious bronchitis virus (IBV) on renal function were evaluated, following primary vaccination in 1-d-old male broilers. 2. Challenge with T-strain IBV decreased body weight and induced kidney hypertrophy and kidney asymmetry. 3. Haematocrit was reduced in birds challenged with the Australian T-strain IBV and plasma uric acid was elevated in unvaccinated birds exposed to the IBV challenge. 4. Challenge with T-strain IBV caused significant increases in urinary water losses, accompanied by decreased urine osmolality and increased fractional excretion of sodium, calcium and potassium. 5. Vaccination at 1-d-old with Vic S-strain IBV provided a limited degree of protection against an heterologous challenge with T-strain IBV at 15 d of age.
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Afanador et al. (1994) studied this question.
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