Why the study?
Does acute bisoprolol administration alter myocardial contractility and total arterial stiffness in patients with overt hyperthyroidism?
Does acute bisoprolol administration alter myocardial contractility and total arterial stiffness in patients with overt hyperthyroidism?
Acute beta1-adrenergic blockade with bisoprolol in overt hyperthyroidism blunts cardiovascular hyperkinesia and normalizes total arterial stiffness primarily by reducing heart rate, rather than altering myocardial contractility.
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Acute bisoprolol may blunt hyperkinesia in hyperthyroidism without altering contractility; leaves open long-term remodeling effects pending RCTs.
Palmieri et al. (2004) studied this question.
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