Why the study?
Does the CRP gene +1444TT genotype increase basal and stimulated CRP levels in army recruits and CABG patients?
Population
n=443 total; comprising 250 male army recruits and 193 coronary artery bypass graft (CABG) patients.
Comparison
Presence of CRP gene +1444TT homozygous genotype vs Presence of CRP gene +1444 C-allele carrier…
Design
Cohort
Follow-up
Up to 96 hours post-exercise and 72 hours postoperatively
Authors
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+1444TT genotype was associated with higher CRP; leaves open implications for CHD prediction and pathogenesis.
Does the CRP gene +1444TT genotype increase basal and stimulated CRP levels in army recruits and CABG patients?
The CRP gene +1444C>T variant is associated with higher basal and stimulated CRP levels, which may have implications for coronary heart disease prediction and pathogenesis.
Brull et al. (2003) studied this question.
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