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July 1, 2013Clinical Transplantation

Mean FEV1 % and 6MWD improved from 26.4% to 88.9% and from 397 to 549 m at 26 wk, respectively (both p < 0.001), with delayed recovery of exercise capacity related to slow recovery of muscle strength.

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Population

50 lung transplant recipients at a single institution between June 2007 and January 2011, mean age 42 years.

Design

Cohort

Follow-up

26 weeks

Authors

JWJames WalshDCDaniel C. ChambersRDRebecca J. Davis

Discussion

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Overview

Rehab should target muscle strength to optimize exercise recovery after lung transplant; hypothesis-generating for randomized confirmation.

Structured PICO

P
Population
50 lung transplant recipients at a single institution between June 2007 and January 2011, mean age 42 (± 13) years.
I
Intervention
Lung transplantation (observational follow-up)
O
Outcome
Changes in lung function (FEV1%), six-min walk distance (6MWD), and quadriceps strength corrected for body weight (QS%) in the first 26 weeks post-transplantsurrogate

Delayed recovery of exercise capacity after lung transplantation is driven by slow recovery of muscle strength rather than delayed improvement in graft function.

Cite This Study

Walsh et al. (2013) studied this question.

synapsesocial.com/papers/6a74486eb06f632524092e67https://doi.org/10.1111/ctr.12163
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predicting 6-Minute Walking Distance in Recipients of Lung Transplantation: Longitudinal Study of 108 Patients2014 · 30 citations
  2. 2Exercise after lung transplant2002 · 2 citations
  3. 3Exercise Limitation in Recipients of Lung Transplants2004 · 51 citations
  4. 4Respiratory and Limb Muscle Function in Lung Allograft Recipients1999 · 60 citations
  5. 5Successfully physical therapy program for functional respiratory rehabilitation after lung transplant surgery – case report2024 · 9 citations