Why the study?
Does a high calcium diet and/or physical exercise reduce blood pressure in spontaneously hypertensive rats?
Population
Spontaneously hypertensive rats, with Wistar-Kyoto rats serving as normotensive controls
Comparison
High calcium diet and/or physical exercise for… vs Normal calcium diet and/or no exercise
Design
Preclinical
Follow-up
23 weeks
Authors
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Hypothesis-generating for calcium in hypertensive models; leaves open human translation and exercise effects.
Does a high calcium diet and/or physical exercise reduce blood pressure in spontaneously hypertensive rats?
In a rat model of hypertension, a high calcium diet attenuated the rise in blood pressure and enhanced arterial potassium relaxation, whereas exercise training did not affect blood pressure.
Kirsimarja Sallinen (1996) studied this question.
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