Key result
Rhinovirus was detected in 100% of hospitalized infants and 60.5% of non-hospitalized infants in the outbreak orphanage compared to 22.5% in the control orphanage, identifying it as the cause of the severe respiratory outbreak.
Observational (n=95)
Yes
Absolute Event Rate: 60.5% vs 22.5%
p-value: p=0.0005
Human rhinovirus is an underappreciated cause of severe, potentially fatal pneumonia in vulnerable infant populations.
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May warrant rhinovirus testing in severe infant outbreaks; observational data leave open broader management implications.
Hải et al. (2012) conducted an observational in Severe acute respiratory infection (n=95). Rhinovirus outbreak exposure (living in outbreak orphanage) vs. Living in control orphanage was evaluated on Rhinovirus positivity by RT-PCR (p=0.0005). Rhinovirus was detected in 100% of hospitalized infants and 60.5% of non-hospitalized infants in the outbreak orphanage compared to 22.5% in the control orphanage, identifying it as the cause of the severe respiratory outbreak.
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