Key result
Isolated aortic valve replacement with 19 mm valves yielded actuarial survival rates of 75% at 5 years and 56% at 10 years, with age >70 years (P=0.0001) and EF <55% (P=0.0305) reducing survival.
Why the study?
Does isolated aortic valve replacement with 19 mm valves provide satisfactory long-term survival?
Cohort (n=202)
Does isolated aortic valve replacement with 19 mm valves provide satisfactory long-term survival?
Aortic valve replacement with 19 mm valves provides satisfactory mid-to-long-term survival, though older age and reduced ejection fraction are significant risk factors for mortality.
Offers acceptable survival benchmarks for 19 mm AVR; leaves open optimal prosthesis selection in high-risk subgroups.
Long-term survival was investigated in 202 patients who underwent isolated aortic valve replacement (AVR) with 19 mm valves. There were 171 women with a mean age of 69+/-9 years and 31 men with a mean age of 64+/-13 years. Patients had a mean body surface area of 1.61+/-0.13 m(2). Patient-prosthesis mismatch was moderate in 196 and severe in six patients. The mean follow-up for all patients was 78 months. There were 79 late deaths. The actuarial survival rates for all patients were 95+/-1% at 1 year, 75+/-2% at 5 years, 56+/-2% at 10 years, 41+/-2% at 15 years, 34+/-3% at 20 years and 34+/-2% at 25 years. Patients over 70 years old had a lower survival rate (P=0.0001). There were significant differences between ejection fraction (EF) >55% and EF <55% (P=0.0305). AVR with 19 mm valves appeared to provide satisfactory mid-term survival. Age and low EF were risk factors for shorter survival.
No takes yet. Share an insight, caveat, or question.
Álvarez et al. (2009) conducted a cohort in Aortic valve disease requiring replacement (n=202). Isolated aortic valve replacement with 19 mm valves was evaluated on Long-term survival. Isolated aortic valve replacement with 19 mm valves yielded actuarial survival rates of 75% at 5 years and 56% at 10 years, with age >70 years (P=0.0001) and EF <55% (P=0.0305) reducing survival.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: