Population
HEp-2 cells
Design
Preclinical
Authors
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TNF-driven IFN-beta transcription in epithelial cells may mediate antiviral effects; leaves open in vivo and clinical translation.
The study demonstrates that TNF induces IFN-beta 1 transcription in HEp-2 cells, substantiating its role as a mediator of TNF's biological antiviral activity.
Jacobsen et al. (1989) studied this question.
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