Key result
Visceral adiposity index was independently correlated with carotid intima-media thickness (ßst 0.07, p=0.0392), suggesting it is a marker of subclinical atherosclerosis in individuals prone to diabetes.
Why the study?
Visceral adiposity index estimates visceral adipose tissue mass and dysfunction, but whether it is associated with subclinical atherosclerosis in individuals free of cardiovascular disease who are at risk for diabetes was unknown.
Cross-Sectional (n=731)
No
Effect estimate: ßst 0.07
p-value: p=0.0392
The visceral adiposity index is independently associated with carotid intima-media thickness in individuals at risk for diabetes, suggesting it may be a useful surrogate marker for subclinical atherosclerosis.
Supports visceral adiposity index evaluation for subclinical atherosclerosis in diabetes-prone patients; hypothesis-generating and should not yet change practice.
AIM: The visceral adiposity index (VAI) has been proposed as an estimate of visceral adipose tissue (VAT) mass and as an indicator of VAT dysfunction. Both parameters are associated with cardiometabolic risk, including insulin resistance. In this study, we investigated whether VAI is associated with subclinical atherosclerosis in subjects who were free of cardiovascular disease but were at risk of developing diabetes mellitus. METHODS: A total of 731 adults with a median age of 47 years old without diabetes mellitus were included in this cross-sectional study. The anthropometric data, blood pressure, and lipid profiles of 398 women and 333 men were measured. All subjects underwent an oral glucose tolerance test, and carotid intima-media thickness (cIMT) was evaluated by ultrasound. Insulin resistance was estimated using the homeostatic model assessment of insulin resistance (HOMA-IR). RESULTS: =0.03, p=0.37) was correlated with cIMT independently of other established cardiovascular risk factors. CONCLUSION: The calculation of VAI may provide a better estimation of subclinical atherosclerosis than the calculation of HOMA-IR.
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Randrianarisoa et al. (2019) conducted a cross-sectional in Prone to diabetes mellitus (n=731). Visceral adiposity index (VAI) vs. Homeostatic model assessment of insulin resistance (HOMA-IR) was evaluated on Correlation with carotid intima-media thickness (cIMT) independently of other established cardiovascular risk factors (ßst 0.07, p=0.0392). Visceral adiposity index was independently correlated with carotid intima-media thickness (ßst 0.07, p=0.0392), suggesting it is a marker of subclinical atherosclerosis in individuals prone to diabetes.
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