Key result
Gluteofemoral adipose tissue demonstrated markedly higher relative release of the lipokine palmitoleate and higher SCD1 expression compared with abdominal subcutaneous adipose tissue.
Observational
Gluteofemoral adipose tissue intrinsically produces and releases more of the insulin-sensitizing lipokine palmitoleate than abdominal subcutaneous fat, potentially explaining its association with reduced cardiovascular and diabetes risk.
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Gluteofemoral fat may confer metabolic protection via palmitoleate; cross-sectional data leave open causal roles for SCD1 in cardiometabolic risk.
Pinnick et al. (2012) reported an observational. Gluteofemoral adipose tissue vs. Abdominal subcutaneous adipose tissue was evaluated on Relative release of palmitoleate (16:1n-7) and SCD1 expression. Gluteofemoral adipose tissue demonstrated markedly higher relative release of the lipokine palmitoleate and higher SCD1 expression compared with abdominal subcutaneous adipose tissue.
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