What question did this study set out to answer?

To compare the clinical, aetiopathogenic, and neuroimaging profiles of stroke on awakening versus stroke while awake, particularly among patients presenting within six hours of symptom recognition.

January 1, 2003Cerebrovascular Diseases

Stroke on Awakening: Looking for a More Rational Management

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Authors

JSJoaquı́n SerenaUniversity of Bern ADAntoni DávalosHospital Universitari Germans Trias i Pujol TSTomás SeguraBaylor College of Medicine

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Implication

Observational registry study reveals similar clinical and imaging features between waking and awake strokes, suggesting potential eligibility for acute reperfusion.

Key Points

To compare the clinical, aetiopathogenic, and neuroimaging profiles of stroke on awakening versus stroke while awake, particularly among patients presenting within six hours of symptom recognition.
Analyzed consecutive patients with acute cerebral infarction enrolled in the Spanish Neurological Society registry (BADISEN).
Evaluated 365 clinical variables, including vascular risk factors, stroke severity, baseline vital signs, and neuroimaging findings, across the total cohort (N=1,248) and a subgroup evaluated within a 6-hour window (N=654).
Of 1,248 patients, 301 (24.1%) had stroke on awakening (SOA) and 947 (75.9%) had stroke while awake (SWA), with both cohorts exhibiting peak onset between 6:01 a.m. and 12:00 noon.
Age, sex, vascular risk factors, admission neurological severity, vital signs, and etiopathogenic subtypes showed no statistically significant differences between SOA and SWA groups overall or within the 6-hour evaluation window.
Among the 654 patients presenting within 6 hours, admission CT scans were normal in 39.4% of SOA patients versus 60.8% of SWA patients, with final imaging revealing territorial infarction in 46.2% and 67.7% of those cases, respectively.

Cite This Study

Serena et al. (2003) studied this question.

synapsesocial.com/papers/6a749e890081fe7b05dbdf1c https://doi.org/10.1159/000070592

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Implication

Observational registry study reveals similar clinical and imaging features between waking and awake strokes, suggesting potential eligibility for acute reperfusion.

Stroke on Awakening: Looking for a More Rational Management

Discussion

Member takes

Implication

Key Points

Cite This Study

Stroke on Awakening: Looking for a More Rational Management

Discussion

Member takes

Implication

Key Points

Cite This Study

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