Relation of blood pressure and body build to left ventricular mass in normotensive and hypertensive employed adults
Key result
BMI, systolic BP, and height independently correlate with LV mass in unmedicated adults.
- P<0.0001
- n=624
Why the study?
Although left ventricular muscle mass increases with large body size, high blood pressure, and obesity, the relative contributions of these and other factors to ventricular mass had not been elucidated.
Population
Unmedicated employed adults (162 normotensive, 145 borderline hypertension, 317 established essential hypertension)
Comparison
Effects of blood pressure, body build, and other clinical factors on left ventricular mass across subgroups
Design
Cross-sectional study
Authors
Discussion
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Implication
Obesity (measured by BMI) is as important a determinant of left ventricular mass as systolic blood pressure in employed adults.
Key Points
- This research aims to explore the relationship between various factors, including blood pressure and body build, and left ventricular mass in adults.
- Echocardiographic assessments of left ventricular mass were conducted on 624 employed adults.
- Participants included 162 normotensive and 462 hypertensive individuals categorized by their blood pressure levels.
- Correlations were analyzed between left ventricular mass and factors including body mass index and blood pressure.
- Body mass index and height were the strongest correlates of left ventricular mass (p < 0.0001).
- Systolic blood pressure showed a weaker correlation (0.001 < p < 0.02) in hypertensive individuals.
- Diastolic blood pressure was a weak predictor of ventricular mass only in established hypertension (p < 0.05).
Study Design
Type
Cross-Sectional (n=624)
Structured PICO
P
Population
624 unmedicated employed adults, including normotensive, borderline hypertensive, and established essential hypertensive individuals, evaluated for correlates of left ventricular mass.
O
Outcome
Echocardiographic left ventricular masssurrogate
Main Result
p-value: p=<0.0001
Obesity (measured by BMI) is as important a determinant of left ventricular mass as systolic blood pressure in employed adults.
Cite This Study
Hammond et al. (1988) conducted a cross-sectional in Normotension and hypertension (n=624). Body mass index and systolic blood pressure was evaluated on Echocardiographic left ventricular mass (p=<0.0001). Body mass index, systolic blood pressure, and height were the most significant independent correlates of left ventricular mass (p<0.0001) in unmedicated employed adults.