Key result
High circulating levels of endothelial- and platelet-derived microparticles are linked to stroke severity, infarct size, and prognosis.
Why the study?
Endothelial activation and altered thrombotic responses predispose to stroke, and microparticles shed from these pathways may serve as biomarkers for cerebrovascular risk and diagnosis.
Are circulating endothelial- and platelet-derived microparticles useful biomarkers for the diagnosis and management of stroke?
Are circulating endothelial- and platelet-derived microparticles useful biomarkers for the diagnosis and management of stroke?
Circulating endothelial- and platelet-derived microparticles show promise as biomarkers for diagnosing stroke and assessing its severity and prognosis.
No takes yet. Share an insight, caveat, or question.
May inform stroke prognostication; leaves open causal role and clinical utility pending prospective validation.
El‐Gamal et al. (2019) conducted a review in Stroke. Circulating endothelial- and platelet-derived microparticles (EMPs and PMPs) was evaluated. High circulating levels of endothelial- and platelet-derived microparticles are linked to stroke severity, infarct size, and prognosis.
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