Why the study?
It was unclear whether pulse pressure, a surrogate marker of arterial stiffness, predicts chronic kidney disease progression in patients with type 2 diabetes mellitus.
Does higher pulse pressure predict chronic kidney disease progression in patients with type 2 diabetes mellitus?
Population
1494 patients with eGFR ≥ 15 ml/min/1.73 m2 and type 2 diabetes mellitus
Comparison
Quartiles of peripheral and aortic pulse pressure
Design
Prospective study
Follow-up
Up to 6 years
Authors
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Pulse pressure may flag higher-risk T2DM patients for closer monitoring; leaves open its added value beyond albuminuria for progression prediction.
Does higher pulse pressure predict chronic kidney disease progression in patients with type 2 diabetes mellitus?
Higher peripheral and aortic pulse pressure independently predicts chronic kidney disease progression in patients with type 2 diabetes mellitus, suggesting its potential utility as a readily available biomarker for renal decline.
Low et al. (2021) studied this question.
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