Population
Isolated rat cardiomyocytes
Comparison
5-amiloride, an NHE inhibitor, with or without… vs Cardiomyocytes not treated with MIA
Design
Preclinical
Authors
Loading...
Increases [Ca2+]i in rat cardiomyocytes; leaves open relevance of NHE inhibition to human calcium dysregulation or therapy.
Inhibition of the sarcolemmal Na+/H+ exchanger with MIA increases basal and KCl-induced intracellular calcium in rat cardiomyocytes through distinct regulatory mechanisms.
Saini et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: