Why the study?
Does tonsillectomy and adenoidectomy reduce nasopharyngeal antibody response to poliovirus in previously immunized children?
Population
40 children previously immunized with live poliovaccine undergoing tonsillectomy and adenoidectomy, plus a…
Comparison
Tonsillectomy and adenoidectomy vs Pre-operative baseline and children with intact…
Design
Cohort
Follow-up
up to 7 months
Authors
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Tonsillectomy may reduce nasopharyngeal antibody levels in immunized children; hypothesis-generating and should not yet change practice.
Does tonsillectomy and adenoidectomy reduce nasopharyngeal antibody response to poliovirus in previously immunized children?
Tonsillectomy and adenoidectomy significantly reduce pre-existing nasopharyngeal γA antibody levels against poliovirus in previously immunized children.
Pearay L. Ogra (1971) studied this question.
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