Why the study?
Does a booster dose of oral poliovirus vaccine improve antibody titers in school children two years after mass vaccination?
Does a booster dose of oral poliovirus vaccine improve antibody titers in school children two years after mass vaccination?
Two years after mass oral poliovirus vaccination, 96% of school children maintained protective antibody titers, with booster doses significantly improving titers for types 2 and 3.
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Sustained seroprotection seen without routine boosters; leaves open whether targeted boosting improves type 2/3 responses in school children.
Martha L. Lepow (1967) studied this question.