Why the study?
Does oral administration of living attenuated poliovirus induce persistent antibodies in children?
Population
26 children in three groups treated since 1950, including infants with transplacental antibodies
Design
Cohort
Follow-up
approximately eight years
Authors
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Antibody persistence at 8 years in small cohort; hypothesis-generating and should not yet change practice.
Does oral administration of living attenuated poliovirus induce persistent antibodies in children?
Oral vaccination with living attenuated poliovirus induces long-lasting antibody persistence up to eight years, suggesting potential for lifelong immunity.
Stanley A. Plotkin (1959) studied this question.
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