Why the study?
Do different schedules of OPV and EIPV vaccines confer long-term immunity to poliovirus in children?
Population
86 children who completed immunization with trivalent poliovirus vaccines at 1 year of age
Comparison
Live attenuated and enhanced potency inactivated… vs Comparison among the four different vaccine…
Design
Cohort
Follow-up
4 years
Authors
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Supports EIPV-inclusive schedules for durable polio immunity in children; leaves open optimal regimens pending randomized confirmation.
Do different schedules of OPV and EIPV vaccines confer long-term immunity to poliovirus in children?
Immunization with combinations of OPV and EIPV confers long-term immunity, with optimal systemic immunity associated with two or more doses of EIPV.
Faden et al. (1993) studied this question.
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