Why the study?
Does oral poliovirus immunization maintain neutralizing antibodies at 4 years in children previously vaccinated with inactivated vaccine?
Population
Children who previously had received inactivated poliovirus vaccine
Design
Cohort
Follow-up
4 years
Authors
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May indicate durable seroprotection after sequential IPV-OPV; leaves open need for efficacy trials and longer follow-up.
Does oral poliovirus immunization maintain neutralizing antibodies at 4 years in children previously vaccinated with inactivated vaccine?
Oral poliovirus immunization provides adequate protection, indicated by persistent neutralizing antibodies, 4 years post-vaccination in children previously receiving inactivated vaccine.
Cesario et al. (1969) studied this question.
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