Why the study?
Does killed poliovirus vaccine provide long-term immunity in a population with no circulating poliovirus?
Population
Vaccinated groups of children (born 1964-1967) and young adults (born 1960-1963) in Sweden
Comparison
Killed poliovirus vaccine vs Comparison between age groups with different…
Design
Cohort
Follow-up
Up to 10-11 years since last booster
Authors
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Reassures on durable IPV seroprotection up to 11 years in polio-free populations; leaves open optimal booster intervals.
Does killed poliovirus vaccine provide long-term immunity in a population with no circulating poliovirus?
Killed poliovirus vaccine provides sustained long-term immunity with minimal decline in antibody titers up to 11 years post-booster in a population without circulating poliovirus.
M Böttiger (1984) studied this question.
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