Population
Swine carotid media strips (less than 500 microM thick), n=9
Comparison
Stimulation with 109 mM K+ for 1 min or longer… vs Identical stretches after 30 min incubation in…
Design
Preclinical
Authors
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Associates latch state with altered yield mechanics in swine carotid; extends animal smooth muscle physiology but leaves open human translation.
In swine carotid media, the onset of the latch state after K+ depolarization is associated with significant increases in yield stress and the length at which yield is observed.
Singer et al. (1986) studied this question.
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