Population
E. coli expressing talin-fusion proteins and heterologous cells expressing chicken talin
Design
Preclinical
Authors
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Hypothesis-generating for talin-vinculin roles in cardiovascular cell adhesion; further studies needed before mechanistic or therapeutic implications.
The study identifies three distinct vinculin-binding sites in the tail segment of the cytoskeletal protein talin, which overlap with sequences required to target talin to focal contacts.
Gilmore et al. (1993) studied this question.
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