Population
Chick vinculin polypeptides expressed as glutathione-S-transferase fusion proteins in Escherichia coli…
Design
Preclinical
Authors
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No immediate clinical implications; leaves open vinculin-talin targeting for cardiac mechanotransduction studies.
The study identifies residues 1-258 as the minimal talin-binding domain in vinculin and highlights the critical role of charged residues 178 and 181 for this interaction.
Gilmore et al. (1992) studied this question.
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