What question did this study set out to answer?

To determine whether on-pump coronary artery bypass grafting leads to greater long-term neurocognitive decline compared to off-pump surgery over a 3- to 5-year follow-up period.

June 4, 2008European Journal of Cardio-Thoracic SurgeryOpen Access

Neuropsychological functioning 3–5 years after coronary artery bypass grafting: does the pump make a difference?☆

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Authors

NSNathalie StroobantGhent University Hospital GNGuido Van NootenUniversité Libre de Bruxelles DBDirk De BacquerPreventive Cardiology

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Implication

Longitudinal study reveals equivalent long-term cognitive decline in on-pump and off-pump bypass patients, indicating heart-lung machines may not drive late impairment.

Key Points

To determine whether on-pump coronary artery bypass grafting leads to greater long-term neurocognitive decline compared to off-pump surgery over a 3- to 5-year follow-up period.
Recruited 74 patients scheduled for coronary artery bypass grafting (54 completed long-term follow-up; mean age 59 ± 7.5 years) undergoing on-pump or off-pump procedures.
Administered seven standardized neuropsychological tests preoperatively, at 6 days, 6 months, and 3 to 5 years postoperatively.
Quantified intraoperative cerebral embolic load via high-intensity transient signals using transcranial Doppler ultrasonography.
At 3 to 5 years after surgery, 30% of patients met criteria for cognitive decline (defined as ≥20% decline on two or more tests), predominantly affecting visual search speed, visual attention, mental flexibility, and non-verbal immediate memory.
Neither the incidence of cognitive dysfunction nor the trajectory of neurocognitive change over 5 years differed significantly between on-pump and off-pump groups.
No significant clinical or surgical predictors of long-term cognitive decline were identified.

Cite This Study

Stroobant et al. (2008) studied this question.

synapsesocial.com/papers/6a758723b47a809cc2e7201e https://doi.org/10.1016/j.ejcts.2008.05.001

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Implication

Longitudinal study reveals equivalent long-term cognitive decline in on-pump and off-pump bypass patients, indicating heart-lung machines may not drive late impairment.

Neuropsychological functioning 3–5 years after coronary artery bypass grafting: does the pump make a difference?☆

Discussion

Member takes

Implication

Key Points

Cite This Study

Neuropsychological functioning 3–5 years after coronary artery bypass grafting: does the pump make a difference?☆

Discussion

Member takes

Implication

Key Points

Cite This Study

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