Why the study?
Are calcium antagonists effective in preventing complications of hypertension and progression of renal disease?
Population
Hypertensive patients, including elderly patients with predominantly systolic hypertension and hypertensive…
Comparison
Long-acting calcium antagonists vs Other classes of antihypertensive drugs
Design
Review
Authors
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Emphasizes BP reduction as the primary driver of benefit in hypertension; leaves open optimal calcium antagonist use for proteinuria beyond BP control.
Are calcium antagonists effective in preventing complications of hypertension and progression of renal disease?
Calcium antagonists are effective antihypertensive agents that reduce cardiovascular events, with their benefits primarily driven by the extent of blood pressure reduction.
Laing et al. (2000) studied this question.
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