Why the study?
Do aliskiren, moxonidine, or hydrochlorothiazide improve endothelial function and blood pressure in adults with previously untreated obesity-related hypertension?
Do aliskiren, moxonidine, or hydrochlorothiazide improve endothelial function and blood pressure in adults with previously untreated obesity-related hypertension?
Renin inhibition with aliskiren improves endothelial function and provides superior blood pressure reduction compared to sympathoinhibition or diuretic therapy in untreated obesity-related hypertension.
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Aliskiren may be prioritized in obesity-related hypertension; extends renin inhibition data to endothelial function.
Dorresteijn et al. (2012) studied this question.
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