Why the study?
Does bicarbonate dialysis compared to acetate-free biofiltration affect electrocardiographic parameters (HRV and QT interval) during hemodialysis?
Population
Hypotension-free hemodialysis sessions (n=24; 12 bicarbonate dialysis and 12 acetate-free biofiltration)
Comparison
Bicarbonate dialysis (BD) vs Acetate-free biofiltration (AFB)
Design
Cohort
Follow-up
During hemodialysis session
Authors
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BD-associated QT and HRV changes should not alter modality selection; leaves open whether AFB improves tolerance in randomized trials.
Does bicarbonate dialysis compared to acetate-free biofiltration affect electrocardiographic parameters (HRV and QT interval) during hemodialysis?
Bicarbonate dialysis is associated with a greater decrease in the low-frequency component of heart rate variability and more pronounced QT shortening compared to acetate-free biofiltration, reflecting worse cardiovascular tolerance.
Severi et al. (2006) studied this question.
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