Key result
Haemodialysis linked to a ~0.27 reduction in QT/QRS ratio, independent of intradialytic electrolyte changes.
Why the study?
The study was conducted to evaluate electrocardiographic changes during haemodialysis and determine their relationship with electrolyte alterations and acid-base balance.
Does haemodialysis alter the index of cardiac-electrophysiological balance in patients with end-stage renal disease?
Population
35 adult patients with end-stage renal disease on maintenance hemodialysis
Comparison
Immediately before vs end of haemodialysis sessions
Design
Cross-sectional analytical study
Authors
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Haemodialysis was associated with reduced QT/QRS ratio in ESRD; hypothesis-generating for arrhythmia risk and needs prospective confirmation.
Cross-Sectional (n=35)
No
Does haemodialysis alter the index of cardiac-electrophysiological balance in patients with end-stage renal disease?
Mean Difference: -0.27
Absolute Event Rate: 4.01% vs 4.28%
p-value: p=0.014
Haemodialysis significantly reduces the index of cardiac electrophysiological balance (QT/QRS and QTc/QRS ratios), independent of intradialytic electrolyte or acid-base changes.
Arshad et al. (2022) conducted a cross-sectional in End-stage renal disease (n=35). Haemodialysis vs. Pre-dialysis baseline was evaluated on QT/QRS ratio (Index of cardiac-electrophysiological balance) (MD -0.27, p=0.014). Haemodialysis significantly reduced the index of cardiac electrophysiological balance (QT/QRS ratio reduced by 0.27, p=0.014), which was not related to intradialytic changes in electrolytes.
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