Population
Animal models including anaesthetized and conscious dogs, and isolated papillary muscles from cats
Comparison
ICI 170777 vs Baseline, isoprenaline, diazoxide, and sodium…
Design
Preclinical
Follow-up
10-12 hours (duration of effect)
Authors
Loading...
Hypothesis-generating for ICI 170777 in heart failure; human trials needed before clinical consideration.
ICI 170777 demonstrates positive inotropic and balanced vasodilator properties in animal models, highlighting its potential for treating congestive heart failure.
Collis et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: