Why the study?
Acute necrotizing encephalopathy is a rare acute encephalopathy characterized by multi-focal brain lesions, severe neurological findings, and accompanying organ dysfunctions.
Population
Nine patients with acute necrotizing encephalopathy of childhood
Design
Single-center study
Authors
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Adds limited case data on childhood ANEC; leaves open need for multicenter studies to guide care.
In a small case series of childhood acute necrotizing encephalopathy, plasmapheresis was suggested as a treatment option to prevent mortality, though survivors still suffered significant neurological sequelae.
Aksoy et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: