What question did this study set out to answer?

To determine the diagnostic accuracy of central aortic blood pressure estimations provided by the noninvasive SphygmoCor system compared with invasive catheter measurements.

March 31, 2010Blood Pressure Monitoring

Validation of the central blood pressure estimation by the SphygmoCor system in Chinese

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Why the study?

Does the SphygmoCor system accurately estimate central blood pressure compared to invasive catheter measurement in patients undergoing coronary angiography?

Population

45 Chinese patients undergoing coronary angiography

Comparison

Central blood pressure estimation using the… vs Ascending aorta blood pressures measured by…

Design

Cross-sectional

Authors

JZJunli ZuoShanghai Jiao Tong University YLYan LiGeneral Cardiology ZYZijun YanShanghai Jiao Tong University

Discussion

Member takes

Implication

May lead to inaccurate central BP estimates in practice; leaves open need for improved noninvasive validation against invasive measures.

Key Points

To determine the diagnostic accuracy of central aortic blood pressure estimations provided by the noninvasive SphygmoCor system compared with invasive catheter measurements.
Evaluated N=45 patients undergoing diagnostic coronary angiography.
Simultaneously recorded invasive ascending aortic pressure via catheter and noninvasive radial artery pulse waves calibrated to oscillometric brachial blood pressure.
Analyzed agreement and discrepancies using paired t-tests, Pearson correlation coefficients, and Bland-Altman plots.
Estimated central systolic blood pressure was numerically lower than invasive catheter measurements (144±29 vs. 148±30 mmHg; P=0.98), with a large standard deviation of difference of 17 mmHg.
SphygmoCor systematically overestimated diastolic pressure compared to catheter measurements (90±15 vs. 74±13 mmHg; P<0.001) and underestimated central pulse pressure by -20±14 mmHg.
Correlation coefficients between catheter and SphygmoCor were r=0.84 for systolic blood pressure, r=0.60 for diastolic blood pressure, and r=0.82 for pulse pressure (all P<0.001).

Structured PICO

Does the SphygmoCor system accurately estimate central blood pressure compared to invasive catheter measurement in patients undergoing coronary angiography?

Population

45 Chinese patients undergoing coronary angiography

Intervention

Central blood pressure estimation using the SphygmoCor system (pulse wave analysis calibrated with oscillometric brachial pressures)

Comparator

Ascending aorta blood pressures measured by invasive catheter

Outcome

Accuracy of central blood pressure estimation (systolic, diastolic, and pulse pressure)surrogate

The SphygmoCor system, when calibrated with oscillometric brachial pressures, does not provide accurate estimations of central blood pressures compared to invasive catheter measurements.

Limitations

Inaccurate measurement of cuff pressure was the major limiting factor for the use of the transfer function

Cite This Study

Zuo et al. (2010) studied this question.

synapsesocial.com/papers/6a7598981eaff9cba9160bfd https://doi.org/10.1097/mbp.0b013e3283386866

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Validation of the central blood pressure estimation by the SphygmoCor system in Chinese

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Validation of the central blood pressure estimation by the SphygmoCor system in Chinese

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider