Why the study?
Do clinical, functional, and HRQL measures predict 5-year survival in elderly patients with chronic heart failure?
Do clinical, functional, and HRQL measures predict 5-year survival in elderly patients with chronic heart failure?
Functional capacity (walk test) and HRQL measures (MLHF) provide long-term prognostic value for 5-year survival in elderly patients with chronic heart failure.
Walk test and HRQL measures may aid 5-year prognostication in elderly HF; leaves open whether integration improves outcomes.
BACKGROUND: The utility of multidisciplinary chronic disease evaluation measures, especially health related quality of life (HRQL), for long long-term prognostic use in elderly patients with heart failure is uncertain. AIM: To report on clinical, functional and HRQL values of deceased and surviving patients of a 6-month RCT of Cardiac Rehabilitation in addition to specialist nurse outpatient clinic at 5 years. METHODS: The original measures (walk test, Borg RPE, MLHF, EuroQol score and vas, biochemistry) were repeated for patients in a satisfactory condition. RESULTS: Five year survival was characterised by significantly better baseline values for LV dysfunction and NYHA class and 6-month values for MLHF, physical function and biochemistry measures. EuroQuol scores were worse than baseline for surviving patients at 5 years, in contrast to MLHF scores. The walk test gave the highest 5-year relative mortality risk, whereas the MLHF gave similar values to the Borg and uric acid measures. Deaths were more evident in normal weight older patients than in younger obese patients. CONCLUSION: Changes in patient measures were evident over 5 years and most differentiated between survivor and deceased groups. In comparison to the use of the MLHF and EuroQuol-vas, the EuroQuol score was limited by impairments of the ageing process.
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Austin et al. (2008) studied this question.
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