Why the study?
Does the combination of batimastat and captopril reduce tumor growth and lung metastases in mice bearing Lewis lung carcinoma?
Does the combination of batimastat and captopril reduce tumor growth and lung metastases in mice bearing Lewis lung carcinoma?
The combination of batimastat and captopril synergistically inhibits tumor growth and lung metastasis in a mouse model of Lewis lung carcinoma.
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Synergistic antitumor effects seen in murine model; hypothesis-generating and requires clinical validation before human translation.
Prontera et al. (1999) studied this question.
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