Key result
In patients with chronic kidney disease on renal replacement therapy, increased left ventricular end-diastolic size was significantly negatively correlated with the physical functioning scale of quality of life (r=-0.30).
Why the study?
The correlation between structural and hemodynamic parameters of the heart and quality of life parameters in chronic kidney disease patients on renal replacement therapy needed evaluation.
Cross-Sectional (n=86)
Effect estimate: r=-0.30
p-value: p=<0.01
The correlation between structural and hemodynamic parameters of the heart and Quality of life (QOL) parameters have been studied in chronic kidney disease (CKD) patients on hemodialysis (HD), continuous ambulatory peritoneal dialysis (CAPD) and kidney transplant recipients (KTR). Patients were divided into three groups according to the type of RRT. CKD stage 3 patients were in the control group. The significant correlation has been founded between the values of the myocardial mass index (LVMI), end-diastolic size (LVEDS), end-diastolic volume (LVEDV), end-systolic size (LVESS), end-systolic volume (LVESV), ejection fraction (LVEF) of the left heart ventricle and QOL among patients on RRT with minimal structural and functional changes in the heart. A negative correlation has been founded between LVMI, LVEDS, LVEDV and physical health component (PF). A decrease in LVEF, as well as an increase in LVESS and LVESV, was associated with the deterioration in both indicators of physical (PF, RP) and psychological health (SF).
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Urazlina et al. (2019) conducted a cross-sectional in Chronic kidney disease (n=86). Renal replacement therapy vs. CKD stage 3 was evaluated on Correlation between left ventricular end-diastolic size (LVEDR) and physical functioning (PF) scale of quality of life (r=-0.30, p=<0.01). In patients with chronic kidney disease on renal replacement therapy, increased left ventricular end-diastolic size was significantly negatively correlated with the physical functioning scale of quality of life (r=-0.30).
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