Why the study?
Does insulin responsiveness of adipose tissue lipoprotein lipase differ between obese and normal weight subjects?
Population
22 obese and 8 normal weight subjects (n=30)
Comparison
Insulin and glucose infusion to maintain… vs Normal weight subjects (n=8)
Design
Other
Follow-up
6 hours
Authors
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May perpetuate obesity via preserved ATLPL response; Level 5 data leave open causality and preclude practice change.
Does insulin responsiveness of adipose tissue lipoprotein lipase differ between obese and normal weight subjects?
Insulin responsiveness of adipose tissue lipoprotein lipase is delayed but preserved in obese subjects, which may contribute to the maintenance of the obese state.
SADUR et al. (1984) studied this question.
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