Why the study?
Does weight reduction and subsequent weight maintenance alter adipose tissue lipoprotein lipase responsiveness in obese women?
Population
9 obese women, mean age 33.4 years, mean BMI 33.9 kg/m2. Excluded if ingesting drugs with known effects on…
Comparison
Weight reduction via hypocaloric formula feeding… vs Baseline (before weight reduction).
Design
Cohort
Follow-up
4 to 6 months
Authors
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May promote post-loss fat regain in obese women; hypothesis-generating for ATLPL-targeted maintenance strategies.
Does weight reduction and subsequent weight maintenance alter adipose tissue lipoprotein lipase responsiveness in obese women?
Weight reduction followed by weight maintenance in obese women significantly increases adipose tissue lipoprotein lipase responsiveness, which may facilitate the rapid reaccumulation of fat stores and weight regain.
Eckel et al. (1987) studied this question.