Key result
Melatonin, chronotherapy, statins, and aliskiren offer potential cardiovascular protection and anti-remodeling benefits beyond standard blood pressure reduction in hypertensive patients.
Design
Review
Authors
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May support adjunctive chronotherapy or melatonin in hypertension; leaves open prospective RCTs for remodeling outcomes.
Respecting circadian variations and utilizing non-traditional agents like melatonin or statins may offer cardiovascular protection beyond standard blood pressure reduction in hypertensive patients.
Šimko et al. (2009) conducted a review in Hypertension. Melatonin and chronotherapy was evaluated. Melatonin, chronotherapy, statins, and aliskiren offer potential cardiovascular protection and anti-remodeling benefits beyond standard blood pressure reduction in hypertensive patients.
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