Population
Rat ventricular myocytes
Comparison
Carboxyeosin (ATPase inhibitor) vs Untreated cells / baseline conditions
Design
Preclinical
Authors
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Does not inform clinical calcium handling; leaves open translation of this Ca2+-ATPase mechanism beyond rat myocytes.
This preclinical study demonstrates the role of a carboxyeosin-sensitive Ca2+-ATPase in regulating resting intracellular calcium concentration in rat ventricular myocytes.
Choi et al. (1999) studied this question.
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