Key result
This review examines the biologic relationship, pathophysiologic differences, and prognostic significance of elevated troponin in acute stroke compared to acute myocardial infarction.
This review provides insights into the biologic relationship, pathophysiologic differences, and prognostic significance of elevated troponin in acute stroke patients.
Clinicians should interpret troponin elevations in acute stroke separately from MI; review leaves open dedicated prognostic trials.
Although the prognostic value of a positive troponin in an acute stroke patient is still uncertain, it is a commonly encountered clinical situation given that Ischemic Heart Disease (IHD) and cerebrovascular disease (CVD) frequently co-exist in the same patient and share similar risk factors. Our objectives in this review are to (1) identify the biologic relationship between acute cerebrovascular stroke and elevated troponin levels, (2) determine the pathophysiologic differences between positive troponin in the setting of acute stroke versus acute myocardial infarction (AMI), and (3) examine whether positive troponin in the setting of acute stroke has prognostic significance. We also will provide an insight analysis of some of the available studies and will provide guidance for a management approach based on the available data according to the current guidelines.
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Dous et al. (2017) conducted a review in Acute stroke with elevated troponin. Elevated troponin was evaluated. This review examines the biologic relationship, pathophysiologic differences, and prognostic significance of elevated troponin in acute stroke compared to acute myocardial infarction.
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