Why the study?
Does exercise training or immobilization alter peak VO2 and DO2 in dog skeletal muscle independent of O2 delivery?
Population
Purpose-bred hounds divided into three groups: control, exercise trained, and immobilized.
Comparison
Exercise training or left hindlimb immobilization. vs Control group (cage confined for 8 wk).
Design
Preclinical
Follow-up
8 weeks
Authors
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Exercise may enhance canine muscle gas exchange independent of delivery; human translation remains untested and should not alter practice.
Does exercise training or immobilization alter peak VO2 and DO2 in dog skeletal muscle independent of O2 delivery?
Exercise training improves functional blood-tissue gas exchange properties of skeletal muscle independent of oxygen delivery, while immobilization does not impair mass-specific peak VO2 or DO2.
Bebout et al. (1993) studied this question.
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