Key result
Hypertension significantly reduced heart rate variability (SDNN) compared to healthy controls (mean difference 25.94, p<0.0001), with no further significant reduction observed in patients who also had type 2 diabetes.
Why the study?
Does hypertension with or without type 2 diabetes mellitus reduce heart rate variability compared to healthy controls?
Cross-Sectional (n=265)
No
Does hypertension with or without type 2 diabetes mellitus reduce heart rate variability compared to healthy controls?
Mean Difference: 25.94 (95% CI 12.8–39.08)
Absolute Event Rate: 101.43% vs 122.03%
p-value: p=<0.0001
Hypertension significantly reduces heart rate variability, and the coexistence of type 2 diabetes mellitus does not appear to cause further significant reduction in this parameter among hypertensive patients.
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Hypertension was associated with reduced HRV; cross-sectional data leave open diabetes interaction and prognostic value.
Nagy et al. (2014) conducted a cross-sectional in Hypertension and Type 2 Diabetes Mellitus (n=265). Hypertension vs. Healthy controls was evaluated on Standard deviation of NN intervals (SDNN) (MD 25.94, 95% CI 12.80-39.08, p=<0.0001). Hypertension significantly reduced heart rate variability (SDNN) compared to healthy controls (mean difference 25.94, p<0.0001), with no further significant reduction observed in patients who also had type 2 diabetes.
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